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Univ. of California, San Francisco
Researchers provide details of new studies and findings in the area of proteomics
July 6th, 2005
New findings from the United States, Germany and Norway describe advances in proteomics. Study 1: Targeted aquaporin-1 gene disruption impairs cell migration and angiogenesis. According to a study from the United States, "aquaporin-1 (AQP1) is a water channel protein expressed widely in vascular endothelia, where it increases cell membrane water permeability(1-3). The role of AQP1 in endothelial cell function is unknown. Here we show remarkably impaired tumor growth in AQP1-null mice after subcutaneous or intracranial tumor cell implantation, with reduced tumor vascularity and extensive necrosis." "A new mechanism for the impaired...
Source: Biotech Week (2005-07-06)
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