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Anadolu University, Eskisehir
Alkylsulfanyltriazoles have inhibition against Mycobacterium tuberculosis
July 6th, 2005
Alkylsulfanyltriazoles have inhibition against Mycobacterium tuberculosis. "The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial compound development. For this purpose, new alkylsulfanyltriazoles were synthesized and evaluated for antituberculosis activity," scientists in Turkey report. "The reaction of thienyl-2-acetic acid with thiocarbohydrazide gave the mercaptotriazoles (II). The 4-amino-5-(2-thienylmethyl)-3-[1-(2-thienyl)-3-aryl) propion-3-yl] sulfanyl-4H-1,2,4-triazole (III) derivatives were synthesized by reacting the...
Source: Biotech Week (2005-07-06)
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