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Anti-Hu paraneoplastic syndrome presented as cranial nerve palsies
August 10th, 2005
Scientists have observed anti-Hu paraneoplastic syndrome presenting as bilateral sixth cranial nerve palsies. "A 62-year-old woman presented with diplopia caused by bilateral sixth cranial nerve palsies. Two weeks later, she had bulbar weakness and ataxia," researchers in Scotland reported. "Brain magnetic resonance imaging showed non-specific abnormalities and spinal fluid was acellular but contained an elevated protein and oligoclonal bands. A paraneoplastic screen showed anti-Hu antibodies. Her clinical condition improved with immunoglobulin and systemic corticosteroid treatment. Breast cancer was diagnosed 21 months later by mammography but there...
Source: Biotech Week (2005-08-10)
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