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Age-Related Macular Degeneration



Revascularization after verteporfin photodynamic therapy is a byproduct of angiogenesis



September 20th, 2006

Revascularization after verteporfin photodynamic therapy (PDT) is a byproduct of angiogenesis.

Researchers in Germany conducted a study "to evaluate the impact of verteporfin PDT on the induction of apoptosis in choroidal neovascular membranes (CNV) secondary to age related macular degeneration."

K. Petermeier and colleagues, University of Tubingen, conducted a "retrospective review of 22 surgically excised CNV. Twelve of these patients had been treated with PDT 3-146 days previously. Apoptotic cells were detected with the TUNEL technique and compared to the expression of CD34 (endothelial cells, EC), CD105 (activated endothelial cells), Ki-67...


Source: Biotech Week (2006-09-20)

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