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Business Update
Four studies affirm significance of Monogram's Trofile HIV co-receptor tropism assay
September 20th, 2006
Monogram Biosciences, Inc. (MGRM) reported that four studies demonstrating the utility and clinical significance of its Trofile co-receptor tropism assay had been presented at the XVI International AIDS Conference in Toronto. The studies suggest the need for and value of phenotypic assays in evaluating co-receptor tropism. Tropism refers to the specific cellular co-receptors (either CCR5 or CXCR4) that individual strains of HIV use to gain access to host cells. Analyzing tropism plays an essential role in determining whether the use of new drugs which target the CCR5 co-receptor (CCR5 antagonists) is likely to be effective in individual HIV-infected patients. ...
Source: Biotech Week (2006-09-20)
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