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Apoptosis
Apoptosis can be induced by aspirin in human colon cancer cells
September 20th, 2006
According to a study from the People's Republic of China, apoptosis can be induced by aspirin in human colon cancer cells. "Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) inhibit proliferation of human colon cancer cells in vitro. Transmission electron microscope detected morphological features of apoptosis in the aspirin-treated (5 mM, 72 h) HT-29 cells in which cyclooxygenoase-2 is catalytically inactive," wrote H.Y. Yin and colleagues, Tsing Hua University. "We investigated aspirin-induced genome-wide expression changes in HT-29 cells and further studied the time- and concentration-dependent expression changes in 374...
Source: Biotech Week (2006-09-20)
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