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Apoptosis
Lung cancer cell apoptosis is induced following adenoviral vector treatment
September 20th, 2006
Recent research from the United States has reported on the induction of apoptosis in human lung cancer cells following treatment with amifostine and an adenoviral vector containing wild-type p53. "Adenoviral delivery of the p53 gene is a potential therapeutic approach for the treatment of lung cancer. Furthermore, amifostine is a cytoprotective agent and recent reports have described its potentiation of chemotherapy's antitumor activity in lung cancer. "Therefore, we wished to investigate the ability of amifostine both alone and in combination with p53-based therapy to induce apoptosis, and to understand the mechanisms by which this apoptosis...
Source: Biotech Week (2006-09-20)
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