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Addiction Medicine



Systemic administration of alcohol to adult rats inhibits Leydig cell activity



October 25th, 2006

Systemic administration of alcohol to adult rats inhibits Leydig cell activity.

According to recently published research from the United States, "Alcohol has been shown to interfere with testosterone (T) release from Leydig cells. However, the mechanisms responsible for this phenomenon, which may include decreased activity of the luteinizing hormone-releasing hormone (LHRH)-LH axis, as well as a direct influence of the drug on the testes, are not fully understood.

"In this work, we investigated the influence of alcohol, administered intragastrically (i.g.) or delivered via vapors, on Leydig cell activity and T release," wrote M. Herman and colleagues...


Source: Biotech Week (2006-10-25)

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