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Adenovirus Vector
Adenoviral vectors encoding bone morphogenetic protein-2 retarded bone formation
October 25th, 2006
Adenoviral vectors encoding bone morphogenetic protein-2 retarded bone formation in sheep. According to a recently published research from Switzerland, "Critical size defects of bone and delayed fracture healing due to metabolic disorders are still problems in orthopedic surgery. Adenoviral vectors encoding bone morphogenetic protein-2 (Ad.BMP-2) have been used to stimulate bone formation in small animals. "The present study evaluated the use of direct adenoviral gene transfer for inducing bone formation in a large animal. Standardized iliac crest defects were created surgically on both sides of the pelvic bone of white mountain sheep. The efficiency...
Source: Biotech Week (2006-10-25)
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