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Allergy & Immunology



Immune defense provides a new link in the evolution of immunity



October 25th, 2006

Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered a unique evolutionary link between the most primitive innate form of immune defense, which has survived in fish, to the more advanced, adaptive immune response present in humans and other mammals.

The finding, which appears in the online version of a recent issue of Nature Immunology, represents an evolutionary step for the mammalian immune system and offers a potential new strategy for developing much-needed fish vaccines.

In the adaptive immune system in mammals, B cells produce antibodies to fight infection. In the more-primitive innate immunity in...


Source: Biotech Week (2006-10-25)

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