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Angiology
Clopidogrel loading ad hoc is effective at reducing P-selectin expression
October 25th, 2006
Ad hoc clopidogrel treatment after stent implantation is effective at reducing platelet P-selectin expression. According to recent research from Hungary, "Stents represent a thrombogenic surface where one of the earliest events is the deposition of platelets. Activated platelets express neoepitopes that enable them to form homo- and heterotypic aggregates and activate the coagulation system." T. Szuk and colleagues, University of Debrecen, wrote, "In this study, we investigated the effects of ad hoc clopidogrel treatment compared to a clopidogrel pretreated group on platelet P-selectin expression. We found that after stent implantation in the ad hoc...
Source: Biotech Week (2006-10-25)
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