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Genetics & Genomics
Research team identifies additional genetic risk factors for Crohn's disease
May 2nd, 2007
An international research team – including investigators from Massachusetts General Hospital (MGH) and the Broad Institute of Harvard University and Massachusetts Institute of Technology – has identified several novel genetic variations associated with the risk of Crohn's disease. One of the identified genes establishes a role for autophagy, a previously unsuspected biological pathway, in Crohn's disease pathology; and the report documents functional studies which establish that this gene is integral to immune responses to intestinal bacteria. The report will appear in the journal Nature Genetics and is receiving early online release. "Our discovery of several new...
Source: Biotech Week (2007-05-02)
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