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Baylor College of Medicine



Gene activity reveals dynamic stroma microenvironment in prostate cancer



June 24th, 2009

As stroma – the supportive framework of the prostate gland – react to prostate cancer, changes in the expression of genes occur that induce the formation of new structures such as blood vessels, nerves and parts of nerves, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Clinical Cancer Research.

In this study, using special techniques and gene chips that allowed them to sample the entire genome, the researchers found changes in 1,141 genes. They were either upregulated – meaning that there was more of the protein with which they were associated than expected – or downregulated, which meant the opposite, said...


Source: Biotech Week (2009-06-24)

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