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Physiology



Findings from Georgetown University provide new insights into physiology



February 3rd, 2010

Data detailed in 'Sex differences in adaptive downregulation of pre-macula densa sodium transporters with ANG II infusion in mice' have been presented. According to recent research from the United States, "An increase in blood pressure (BP) due to angiotensin II (ANG II) infusion or other means is associated with adaptive pressure natriuresis due to reduced sodium reabsorption primarily in proximal tubule (PT) and thick ascending limb (TAL). We tested the hypothesis that male and female mice would show differential response to ANG II infusion with regard to the regulation of the protein abundance of sodium transporters in the PT and TAL and that these responses would be modulated by...


Source: Biotech Week (2010-02-03)

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