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Androgen-Insensitivity Syndrome

Researchers from Michigan State University Publish New Studies and Findings in the Area of Androgen-Insensitivity Syndrome

Published in Biotech Week, October 19th, 2011

2011 OCT 19 -- According to the authors of recent research published in the journal Hormones and Behavior, "Testosterone influences the hypothalamic-pituitary-adrenal axis, anxiety-related behavior, and sensorimotor gating in rodents, but little is known about the role of the androgen receptor (AR) in mediating these influences. We compared levels of the stress hormone corticosterone at baseline and following exposure to a novel object in an open field in wild type (wt) male and female rats, and male rats with the testicular feminization mutation (Tfm) of the AR, which disables its function."

"Basal corticosterone was equivalent in all groups, but...

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