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Graft-Versus-Host Disease

Investigators at Cornell University Target Graft-Versus-Host Disease

Published in Biotech Week, November 9th, 2011

2011 NOV 9 -- According to the authors of a study from New York City, New York, "Factors contributing to infection risk after cord blood transplantation (CBT) include the use of anti-thymocyte globulin (ATG), prolonged neutropenia, and failure to transfer immunity. In the present study, we investigated the potential of double-unit CBT without ATG to reduce the risk of infection and evaluated the nature of serious infections in the first year after CBT using this approach."

"Seventy-two predominantly adult patients underwent CBT for hematologic malignancies; of these, 52 patients received myeloablative conditioning, and 20 received nonmyeloablative...

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