Addiction Medicine
Studies in the Area of Addiction Medicine Reported from Scripps Research Institute
Published in Biotech Week, November 16th, 2011
2011 NOV 16 -- According to the authors of a study from La Jolla, California, "Endogenous cannabinoids (eCBs) are retrograde messengers that provide feedback inhibition of both excitatory and inhibitory transmission in brain through the activation of presynaptic CBI receptors. Substantial evidence indicates that eCBs mediate various forms of short- and long-term plasticity in brain regions involved in the etiology of addiction."
"The present review provides an overview of the mechanisms through which eCBs mediate various forms of synaptic plasticity and discusses evidence that eCB-mediated plasticity is disrupted following exposure to a variety of abused...
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Source: Biotech Week (2011-11-16)
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