Hematopoietic Cells

Human Umbilical Cord Blood May Be Source for Gene Delivery

Published in Blood Weekly, February 20th, 1995

Researchers from Indiana reported that their data suggest that cord blood may be a promising source for efficient gene delivery to the human hematopoietic system.

David A. Williams and Thomas Moritz, Indiana University School of Medicine, Indianapolis, stated that they identified a chymotryptic fragment of the extracellular matrix molecule fibronectin (FN 30/35), to which primitive hematopoietic cells adhere. The researchers stated that their findings suggest that the use of the FN 30/35 fibronectin molecule may offer a clinically applicable protocol to achieve efficient gene delivery to the human hematopoietic system ("Umbilical Cord Blood Stem Cells as Targets for...

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Source: Blood Weekly (1995-02-20)

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