"Absence of Hepatitis A Virus Transmission by High-Purity Solvent Detergent Treated Coagulation Factor Concentrates in Scottish Haemophiliacs."

According to the authors' abstract of an article published in British Journal of Haematology, "Recent reports of hepatitis A virus (HAV) infection in haemophiliacs receiving high-purity solvent detergent (HP.SD) treated factor VIII concentrates have brought into question the efficacy of this virucidal method for inactivating HAV. To assess whether HAV may have been transmitted by HP.SD concentrates, we compared seroprevalence in haemophiliacs with different disease severity, sought evidence of seroconversion to HAV since introduction of HP.SD products, and directly examined concentrates for HAV RNA by PCR. Our data suggest that Scottish haemophiliacs are not being infected with HAV by...

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