Conference Coverage

Increased HIV Copy Number Correlated with Clinical Progression

Published in Blood Weekly, March 6th, 1995

A twofold increase in plasma HIV RNA copy number is associated with a 17-fold increase in risk of clinical progression, according to data presented at the Nineteenth AIDS Clinical Trial Group (ACTG) Meeting, held February 18-22, 1995, in Washington, D.C.

Recent advances in technology and new insights into HIV pathogenesis have led to the collection and interpretation of virologic data in ACTG studies.

In a plenary address to the ACTG, Harvard researcher Clyde Crumpacker reported analyses of such data obtained in the ACTG 116A clinical trial, which compared AZT monotherapy to ddI monotherapy. Crumpacker's address represents the first report of...

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Source: Blood Weekly (1995-03-06)

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