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Biological Therapy

Diphtheria Toxin-Related Cytokine Fusion Proteins: A New Therapeutic Approach

Published in Blood Weekly, April 17th, 1995

Dr. John R. Murphy, Professor of Medicine in Molecular Genetics and Chief of the Section of Biomolecular Medicine at Boston University Medical Center Hospital in Boston, Massachusetts, presented updated information about the use of diptheria toxin-related cytokine fusion proteins as a form of biologic therapy at the American Cancer Society's 37th Science Writers Seminar, March 26, 1995.

Dr. Murphy explained in his briefing that the process known as receptor-mediated endocytosis provides an extremely efficient pathway for cells to internalize membrane bound macromolecules. As receptor-mediated endocytosis is a universal process, he reports that it is not surprising that...

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