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International/France - HCV Genotypes in Donors

"Hepatitis C Virus Genotypes in French Blood Donors."

Published in Blood Weekly, May 15th, 1995

According to the authors' abstract of an article published in Journal of Medical Virology, "The prevalence of different hepatitis C virus (HCV) genotypes in HCV infected individuals and the relation between the HCV genotypes and the source of the infection are controversial. The aim of this study was to determine the HCV genotypes in French blood donors. Fifty-one anti-HCV positive blood donors were studied with detectable serum HCV RNA by nested polymerase chain reaction (PCR) using primers derived from the 5' non-coding region. For genotyping HCV, we used a method based on analysis of the restriction fragment length polymorphisms (RFLP) after amplification by PCR of the HCV...

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