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Research Agreement To Develop Clotrimazole for Sickle Cell Anemia

Published in Blood Weekly, July 24th, 1995

Sheffield Medical Technologies Inc., New York, New York, announced that it has entered into an option and sponsored research agreement with Children's Hospital, Boston, Massachusetts, to develop clotrimazole and its metabolites for the treatment of sickle cell anemia.

The option includes exclusive rights to an issued U.S. patent covering clotrimazole for this use, as well as rights to data from preclinical and pilot clinical studies conducted to date.

Clotrimazole has a long history of use in humans as an antifungal agent. The rationale for using clotrimazole to treat sickle cell anemia is based on its ability to prevent the dehydration of red blood...

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