"Detection of Hepatitis C Viral RNA: Comparison of Amplicor Single PCR and Nested Set PCR Processes with HCV Serology for Hemodialyzed Patients."

According to the authors' abstract of an article published in Cellular and Molecular Biology, "Multicentre quality control studies demonstrated that optimization and standardization of HCV RNA reverse transcription polymerase chain reaction (RT-PCR) amplification techniques were possible: thus, a nested HCV RNA RT-PCR assay was described as a reliable tool for the detection of hepatitis C viral RNA. Besides this, another procedure, the Amplicor(TM) HCV RNA qualitative test, a standardized RT-PCR assay, became available. In order to assess the relationship between seropositivity and potential infectivity and to compare both RT-PCR assays, all patients undergoing maintenance hemodialysis...

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