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Immunology

Malaria Protection May Be Due to Range of Phenotypic Variation

Published in Blood Weekly, October 9th, 1995

Resistance to malaria among a group living in central India may be associated with a range of phenotypic variation instead of any single protective mutation.

P.H. Reddy, Perinatal Center, University College London Medical School, London, United Kingdom, and colleagues studied the prevalence and molecular quality of hereditary anemias in the Baiga, a tribe in central India ("Hereditary Anaemias and Iron Deficiency in a Tribal Population (the Baiga) of Central India," European Journal of Haematology, August 1995;55(2):103-109).

People living in areas endemic for falciparum malaria commonly have hereditary anemias because such conditions confer...

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