"Alpha Interferon Alone and in Combination with Ribavirin for Hepatitis C Virus (HCV) Infection in Multiply Transfused Thalassaemic Patients."

According to an abstract submitted by the authors to the 37th Annual Meeting of the American Society of Hematology, held December 1-5, 1995, in Seattle, Washington, "Progressive liver damage is a major problem for thalassaemic patients, and is often due to a combination of chronic HCV infection and hepatic toxicity from transfusional iron overload. Therapy aimed at clearing HCV infection may retard or prevent clinical complications. We have treated 28 HCV RNA positive, multiply transfused beta thalassaemia major patients with interferon-alpha (Intron-A, Schering-Plough) at 3-6 mega units thrice weekly for 6-12 months. Nine patients (32%) are currently HCV RNA negative with median...

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