Blood Banking (Blood Groups)

Phase II Trials Planned for RBCs Converted to Group O

Published in Blood Weekly, February 5th, 1996

Red cells that have been converted from group B to group O were safe and efficacious when transfused to individuals with group O or group A blood.

Methods to enzymatically convert group A and group B red cells to group O red cells are being developed.

The availability of such converted red cells in a clinical setting can diminish problems associated with shortages of group O red cells. In addition, the number of group A or group B units that are outdated or discarded might be reduced, said L.L. Lenny, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, and colleagues ("Multiple-Unit and Second Transfusions of Red Cells...

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Source: Blood Weekly (1996-02-05)

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