Published in Blood Weekly, February 5th, 1996
c-kit is a growth factor receptor on hematopoietic stem/progenitor cells. It is expressed on murine pluripotential stem cells capable of reconstituting all hemopoietic lineages as well as in human hematopoietic progenitor cells. In addition, its expression is restricted to stem/progenitor cells and is not expressed on its committed progeny except for mast cells.
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