Conference Coverage (CHI Vaccines)

Chimeric Mengo Virus Vaccines for HIV, Malaria, and More

Published in Blood Weekly, April 22nd, 1996

A very small virus promises to have a very large impact on vaccinology.

Vaccines employing the attenuated virus as a vector are already being developed for HIV disease and malaria; other applications are under consideration.

The attenuated virus itself has been used in veterinary applications to eradicate an encephalomyocarditis virus (EMCV) epidemic in a U.S. baboon colony and is currently being tested in an effort to halt a cardiovirus epizootic among African elephants.

The virus is Mengo virus, a cardiovirus that primarily infects mice. But the virus is easily transmissible to anything that ingests an infected rodent. In the...

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Source: Blood Weekly (1996-04-22)

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