"Fetal Transplantation Therapy: Immunophenotypic Characterization of Fetal Liver Hematopoietic Stem Cells in the Second Trimester."

According to an abstract submitted by the authors to the 43rd Annual Meeting of the Society for Gynecologic Investigation, held March 20-23, 1996, in Philadelphia, Pennsylvania, "Fetal tissues are less immunogenic and less immunocompetent than tissues from more mature sources. However, the most suitable gestational age for harvesting hematopoietic stem cells for transplantation therapy is yet to be defined. Tolerance of transplants is largely mediated by histocompatibility antigens (HLA). We immunophenotypically characterized fetal liver hematopoietic stem cells in the second trimester to determine whether the expression of HLA A, B, C and HLA DR (Type I and Type II major...

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