Multidrug Resistance

Oncolysin B Eliminated MDR Tumors in Mice

Published in Blood Weekly, May 13th, 1996

Researchers from ImmunoGen, Inc., Cambridge, Massachusetts, published data demonstrating that Oncolysin B overcame and eliminated multi-drug resistance in tumors.

The results, published in the May 1, 1996, issue of Blood, further showed that mice given drug-resistant human tumors were completely cured when treated with Oncolysin B followed by a combination of conventional chemotherapeutic agents. These findings are especially important because multi-drug resistance in tumors is a major limitation in the successful treatment of many cancers.

ImmunoGen is conducting a Phase II human clinical study to test the potential benefits of using Oncolysin B in...

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Source: Blood Weekly (1996-05-13)

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