"Localization of Human Herpes-Like Virus Type 8 in Vascular Endothelial Cells and Perivascular Spindle-Shaped Cells of Kaposi's sarcoma Lesions by in situ Hybridization."

According to the authors' abstract of an article published in American Journal of Pathology, "Kaposi's sarcoma (KS) is a neoplasm that develops as multifocal lesions characterized by a histological picture that includes irregularly shaped vascular spaces surrounded by perivascular and interstitial spindle-shaped cells, extravasated erythrocytes, and an inflammatory mononuclear cell infiltrate. Recently, the DNA sequences of a novel human gamma-herpesvirus-like (HHV-8) agent have been detected by polymerase chain reaction ire KS associated with acquired immune deficiency syndrome (AIDS-KS), classical KS, and African endemic KS. The present study was done to identify the specific cells...

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