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Tissue Engineering

Constructed Lamb Heart Valve Leaflets Histologically Resemble Native Tissue

Published in Blood Weekly, July 22nd, 1996

Tissue engineered autologous heart valve leaflets are feasible, experimental results have demonstrated.

C.K. Breuer, Harvard Medical School, Boston, Massachusetts, and colleagues constructed tissue engineered lamb heart valve leaflets that histologically resembled native valve leaflet tissue ("Tissue Engineering Lamb Heart Valve Leaflets," Biotechnology and Bioengineering, June 5, 1996;50(5):562-567).

The construction of a tissue engineered heart valve has numerous potential advantages over current therapy for the replacement of heart valves.

"These advantages include the avoidance of anticoagulant therapy, the potential for...

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