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Hypertension Gene Therapy

Delivery of Therapeutic cDNA Modulates High Blood Pressure

Published in Blood Weekly, July 29th, 1996

Control of chronic AngII-dependent hypertension via retroviral-mediated gene transfer in an animal model.

Shridhar N. Iyer et al., from the University of Florida, presented data at the 10th International Congress of Endocrinology, sponsored by the International Society of Endocrinology and the Endocrinology Society, held June 12-15, 1996, in San Francisco, California, which demonstrated the possibility of a gene therapy approach to treat chronic hypertension in vivo (abstract "Retroviral-Mediated Delivery of Antisense cDNA of AT1 Receptor Attenuates Development of High Blood Pressure in the Spontaneously Hypertensive Rat").

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