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Anticoagulants

Gusto IIb/Hirudin Provides Advantage Over Heparin as Blood Thinner

Published in Blood Weekly, September 30th, 1996

Patients with acute coronary syndromes who were given the anticoagulant hirudin were less likely to incur a heart attack or death than a similar group of patients who were treated with heparin.

The finding is among the results of the second Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes (Gusto IIb) study published in the September 12, 1996, issue of the New England Journal of Medicine.

The 12,142-patient study compared heparin, the intravenous anticoagulant routinely used today, with hirudin, a genetically engineered compound that is not yet commercially available. Hirudin is a protein derived from leech saliva, the...

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