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Sickle Cell Disease

"Delayed Hemolytic Transfusion Reaction in Sickle Cell Disease."

Published in Blood Weekly, November 18th, 1996

According to the authors' abstract of an article published in American Journal of the Medical Sciences, "This article reports the details of delayed hemolytic transfusion reactions in four patients with sickle cell disease. These cases demonstrate the characteristics of the reactions, the significant risks involved, and the principles useful in diagnosis and treatment. Patients with sickle cell disease are at particular risk for delayed hemolytic transfusion reactions because they may be transfused at intervals over many years; they frequently form alloantibodies because of antigenic differences from the donor population; and they may receive emergency care in different hospitals where...

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