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Blood Banking (HCV)

"Prevalence of Hepatitis C Virus and Genotype Distribution in an Australian Volunteer Blood Donor Population."

Published in Blood Weekly, March 17th, 1997

According to the authors' abstract of an article published in Transfusion, "Background: This study was undertaken to assess the prevalence of hepatitis C virus (HCV) antibody and RNA in first-time blood donors and to examine the HCV genotype distribution. Study Design and Methods: A third-generation enzyme-linked immunosorbent assay (ELISA) was used to screen 34,725 donors for HCV antibodies. Donors who were repeatedly reactive were tested in two immunoblot assays-a second-generation and a third-generation recombinant immunoblot assay-as well as by a polymerase chain reaction (PCR) assay. PCR-positive donors were genotyped. All samples were screened for alanine...

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