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Diagnostics (HCV)

"Molecular Biological Studies on Indian Strains of Hepatitis C Virus."

Published in Blood Weekly, May 5th, 1997

According to an abstract submitted by the authors to the 4th International Meeting on Hepatitis C Virus and Related Viruses, Molecular Virology and Pathogenesis, held March 6-10, 1997, in Kyoto, Japan, "We have developed a sensitive polymerase chain reaction (PCR) method for detecting Indian strains of HCV using primers designed from the minimum variable region of the HCV genome. Commonly used primers for detecting US and Japanese strains of HCV were found unsuitable for Indian strains because of genetic variations. We show also that the method we have developed can detect the presence of HCV in ELISA negative (using commercially available kits) patients who had received more recent...

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