"Detection of HIV-1 RNA Subtypes with Transcription-Mediated Amplification."

According to an abstract submitted by the authors to the 97th General Meeting of the American Society for Microbiology, held May 4-8, 1997, in Miami Beach, Florida, "Current detection of HIV-1 infection in the blood bank setting is based on serologic screening for viral antibodies and p24 antigen. Addition of a test to detect HIV-1 RNA would allow earlier detection of HIV-1 infection, reducing infections by blood transfusion. A major challenge for the development of assays for this virus is its high degree of genetic diversity, which includes two major groups M and O, and several subtypes or dades: A to I. To provide a highly sensitive and simple assay able to detect all HIV-1...

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