Conference Coverage (SPIRAT/(NCDDG-HIV)

Compartmentalization of HIV a Problem for Drug-Trials

Published in Blood Weekly, July 14th, 1997

Potent new therapies attack HIV in the blood and lymph nodes, but it remains unclear whether the virus lurks in other nooks of the body.

Evaluating virus levels in such areas remains a challenge for the design of clinical trials.

"It would be a Pyrrhic victory to successfully treat HIV in the blood and not reach it in the CNS [central nervous system] and testes," said Robert W. Coombs of the University of Washington, Seattle.

Coombs discussed the compartmentalization of HIV between the blood and the genital tract in an address to "New Opportunities for HIV Therapy - From Discovery to Clinical Proof-of-Concept," the 2nd Joint...

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Source: Blood Weekly (1997-07-14)

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