Transfusion
Semi-Closed Hollow-Fiber Bioreactor System Is Efficient
Published in Blood Weekly, July 28th, 1997
These cells have great potential in clinical gene therapy, said Raji Shankar, University of Minnesota Medical School, Minneapolis, Minnesota, and colleagues ("Retroviral Transduction of Peripheral Blood Leukocytes in a Hollow-Fiber Bioreactor," Transfusion, July 1997;37:685-690).
Shankar et al. tested a semi-closed hollow-fiber reactor for culturing and transducing lymphocytes. They used Hunter syndrome as a model and used the L2SN retroviral vector.
They noted that other researchers have used hollow-fiber...
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Source: Blood Weekly (1997-07-28)
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