Transplantation
Plasmid-Mediated Gene Transfer into the Thymus Possible
Published in Blood Weekly, August 11th, 1997
J.W. Kippler et al. demonstrated earlier that the thymus plays a major role in the development of self-tolerance (Cell 1987;49:273) and G. Ellison et al. demonstrated that the thymus plays a major role in the induction of acquired tolerance to exogenous antigens almost three decades ago (Immunology 1970;105:322). Subsequently, T. Quian et al. demonstrated that the successful induction of donor-specific unresponsiveness to rat islet or renal allografts could be made through the intrathymic injection of...
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Source: Blood Weekly (1997-08-11)
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