Prognosis (HCV)

Immunosuppression Worsens IVIG Acquired HCV Disease Course

Published in Blood Weekly, September 1st, 1997

Immunosuppressed patients with intravenous immunoglobulin-acquired hepatitis C virus infection tend to have a worse outcome than patients with intact immune systems, according to a report from Italy.

"We found that in hematologic patients with coexisting immunodeficiency, intravenous immunoglobulin-induced HCV infection can frequently lead to irreversible liver failure, which markedly worsens their prognosis," researcher Giuseppe Rossi and colleagues wrote ("Outbreak of Hepatitis C Virus Infection in Patients with Hematologic Disorders Treated with Intravenous Immunoglobulins: Different Prognosis According to the Immune Status," Blood, 1997;90:1309-1314).

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Source: Blood Weekly (1997-09-01)

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