Cytomegalovirus
"Plasma Polymerase Chain Reaction for Cytomegalovirus DNA after Allogeneic Marrow Transplantation - Comparison with Polymerase Chain Reaction using Peripheral Blood Leukocytes, pp65 Antigenemia, and Viral Culture.
Published in Blood Weekly, September 8th, 1997
According to the authors' abstract of an article published in Transplantation, "In a prospective longitudinal study, detection of cytomegalovirus (CMV) DNA in plasma (plasma polymerase chain reaction [PCR]) was compared with PCR of CMV DNA in peripheral blood leukocytes (PBL PCR), the CMV pp65 antigenemia assay, and viral cultures from blood, urine, and throat of 29 patients, 14 of whom received pp65 antigenemia-guided early ganciclovir treatment and 15 of whom received ganciclovir at engraftment. Among 328 blood samples tested by all methods, PBL PCR was the most sensitive test, followed by the pp65 antigenemia assay, plasma PCR, and viremia. In the 14 patients who received pp65...
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Source: Blood Weekly (1997-09-08)
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