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Human Herpesvirus 8

Dual Herpesviral Infection Found in Human Neoplasm

Published in Blood Weekly, September 15th, 1997

A dual herpesviral infection offers a model for studying viral interactions.

Primary effusion (body cavity-based) lymphoma (PEL) is a subtype of malignant lymphoma that shows distinctive clinical and biological features - in particular, Kaposi's sarcoma-associated herpesvirus (KSHV) infection. Most cases also are associated with Epstein-Barr virus (EBV).

"To the best of our knowledge, this is the first example of a dual herpesviral infection consistently associated with a specific human neoplasm and thereby provides a unique model to study viral interactions," wrote Marcelo G. Horenstein, the New York Hospital-Cornell Medical Center, New York, New...

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