Published in Blood Weekly, September 22nd, 1997
Despite similar structural and enzymatic properties, however, variations in tissue specific expression and subtle differences in enzyme activity across species may exist, said David Gailani, and colleagues, Vanderbilt University School of Medicine, Nashville, Tennessee ("A Comparison of Murine and Human Factor XI," Blood, 1997;90:1055-1064).
"Our data show that murine and human factor XI are structurally homologous and have similar enzymatic properties, particularly in regard to the activation of factor IX," wrote Gailani et al. "The autoactivation studies in the...
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