Transplantation (Bone Marrow)

Fatal HBV Reactivation a Danger with Bone Marrow Transplant

Published in Blood Weekly, October 20th, 1997

A disturbance in the balance between hepatitis B virus replication and immune control after bone marrow transplantation may result in fatal reactivation of hepatitis B.

Researcher M. Caselitz and colleagues of Hannover, Germany, presented the case of a 27-year-old male leukemia patient who was a chronic hepatitis B carrier and who developed fulminant hepatitis B after allogeneic bone marrow transplantation from his hepatitis B immune donor-brother ("Hepatitis B Associated Liver Failure Following Bone Marrow Transplantation," Journal of Hepatology, September 1997;27:572-577).

The risk of chronic hepatitis B infection in patients undergoing bone marrow...

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Source: Blood Weekly (1997-10-20)

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