Blood Banking (Screening)

Anti-E2 Detection Is Useful in HCV Diagnosis in Seroconverting Individuals

Published in Blood Weekly, October 20th, 1997

The use of a hepatitis C virus (HCV) envelope (E2) recombinant antigen did not improve early detection of seroconversion.

Mina Psichogiou, M.D., Athens University Medical School, Athens, Greece, and colleagues published their study in the journal Transfusion ("Immunologic Events during the Incubation Period of Hepatitis C Virus Infection: the Role of Antibodies to E2 Glycoprotein," Transfusion, 1997;37:858-862). They investigated the early immunologic changes in HCV infection, comparing the reactivity to various HCV antigens in seroconverting individuals, and evaluating whether the use of E2 recombinant antigen of HCV, expressed in mammalian cells, would significantly...

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Source: Blood Weekly (1997-10-20)

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