Restenosis (Therapy)

Retinoic Acid Tested As Treatment In Blood Vessels

Published in Blood Weekly, October 27th, 1997

Whenever a blood vessel is damaged - either by the effects of cigarette smoking or hypertension, or even as the result of an operation that removes atherosclerotic plaque or revascularizes a limb or transplanted organ - it begins to heal itself.

The blood vessel activates a complex cascade of physiological events that involve the accumulation of fatty substances, inflammation, and proliferation of smooth muscle cells at the site of the wound and the coagulation of blood cells as they travel past the injury. The healing process results in restenosis, however - as the diameter of the interior of the blood vessel narrows, the vessel wall contracts in size, and the...

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Source: Blood Weekly (1997-10-27)

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