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Surgery

Fibrin-Based Tissue Adhesives Reduce Bleeding, Promote Healing

Published in Blood Weekly, October 27th, 1997

For years, physicians in European countries, Canada, and Japan have used tissue adhesives made from fibrin and thrombin, components of the body's natural healing process, for wound closure and wound healing.

These adhesives are not available commercially in the U.S., however, because the U.S. Food and Drug Administration (FDA) has been concerned about the risk that these adhesives, which are formed from plasma collected from hundreds of donors, might spread viral diseases such as hepatitis or AIDS, according to William D. Spotnitz, MD, FACS.

Dr. Spotnitz, professor of surgery and director of the Tissue Adhesive Center at the University of Virginia...

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